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Axxam scientists perform compound profiling analyses for a number of attractive pharmaceutical target classes. More than 200 functional cell-based and biochemical assays optimized for state-of-the-art detection systems, fluorescence- and luminescence-based, are available. The sensitivity of the assays ensures detection of even minor differences in activity between compounds to facilitate ultimate compound selection for your drug development programs.
Functional assays are available for the following target classes:
- GPCRs
- Ion Channels
- Transporters
- Ion Exchangers
- Nuclear Hormone Receptors
- Tyrosine Kinase Receptors
- Enzymes
Before we commence the compound profiling analysis, you will receive a detailed report describing the assay including:
- assay principle
- readout system and instrumentation used for signal recording
- pharmacology of the target
- parameters optimized for compound screening.
A combination of liquid-handling stations and multi-channel pipette systems permit a high degree of flexibility in the experimental design of a compound profiling project that may include semi-robotic analysis of hundreds of compounds.
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