Quality comes first at Axxam when developing cell-based assays for our customers. Choosing Axxam to develop your cell-based assay means much more than just receiving a vial of frozen cells.
Click on the link below to see more details on the process of cell-based assays development at Axxam.
Axxam began its existence as a center focused exclusively on the development of high quality assays for HTS. We have maintained our high quality standards and built upon this experience over the years and added technology to become a leader in the field, as demonstrated by our technologies, publications and growing list of partners
We can choose among a variety of different reporter genes and signal detection methods to configure the assay. The target gene is stably expressed in the most suited recipient cell line and our experience range from expression of easy GPCR target up to complex multi subunit ion channels. Detection systems include both fluorescence and luminescence with assays optimized for standard 96-, 384- and 1536-MTP formats.
Axxam’s assays must satisfy the highest standards for HTS, with an emphasis on:
- Signal-to-background ratio
- Standard deviation
- Z' factor
- Stability of the signal over the duration of the assay
- Stability of the assay over the duration of the screening campaign
- Consistent automation
- Miniaturization up to 1536-MTP format
On completion of assay configuration and optimization at Axxam one of our scientists will spend a full working week transferring and adapting the assay to your facilities and making sure the assay functions as well in your hands as it did in ours.
